Kim, Hyuk-Soon

Professor Hyuk-Soon Kim, PhD

Biographical Information

Hyuk Soon Kim attended the Konkuk University obtaining a B.Sc. in Biochemistry, M.Sc., and Ph.D. in Medicine. He worked as an assistant professor at School of Medicine, Konkuk Universityin Seoul, Korea (2013 - 2020) and is currently employed as an assistant professor in the Graduate School of Dong-A University in Busan, Korea since 2020. He has published over 45 peer-reviewed papers and several book chapters on immunology and general biology. His current interests are the mechanism of regulatory immune cells, including regulatory T cells (Tregs), regulatory B cells (Bregs), regulatory natural killer cells (NKregs) and regulatory innate lymphoid cells (ILCreg) in various immune disorders as allergy, autoimmune, and cancers.

Ten selected published papers

1. Kim, H.S., Lee, M.B., Lee, D., Min, K.Y., Koo, J., Kim, H.W., Park, Y.H., Kim, S.J., Kim, Ikutani, M., Takaki, S., Y.M., Choi, W.S. The regulatory B cell-mediated peripheral tolerance maintained by mast cell IL-5 suppresses contact hypersensitivity. Science Advances. 2019 Jul 17;5(7):aav8152.
2. Cho, M., Lee, J.E., Lim, H., Shin, H.W., Khalmuratova, R., Choi, G., Kim, H.S., Choi, W.S., Park, Y.J., Shim, I., Kim, B.S., Kang, C.Y., Kim, J.O., Tanaka, S., Kubo, M., Chung, Y. Fibrinogen-cleavage products and TLR4 promote the generation of programmed cell death 1 ligand 2(PD-L2)+ dendritic cells in allergic asthma. Journal of Allergy and Clinical Immunology. 2018 Aug;142(2):530-541.e6.
3. Kim, H.S., Nam, S.T., Mun, S.H., Lee, S.K., Kim, H.W., Park, Y.H. Kim, B., Won, K.J., Kim, H.R., Park, Y.M., Kim, H.S., Beaven, M.A., Kim, Y.M., Choi, W.S. DJ-1 controls bone homeostasis through the regulation of osteoclast. Nature Communications. 2017 Nov 15;8:1519.
4. Kim, H.S., Jang, J.H., Lee, M.B., Jung, I.D., Kim, Y.M., Park, Y.M., Choi, W.S. A novel IL-10-producing innate lymphoid cells (ILC10) in a contact hypersensitivity mouse model. BMB Reports. 2016 May;49(5):293-6.
5. Kim, A.R., Kim, H.S., Kim, D.K., Nam, S.T., Kim, H.W., Park, Y.H., Lee, D., Lee, M.B., Lee, J.H., Kim, B., Beaven, M.A., Kim, H.S., Kim, Y.M., Choi, W.S. Mesenteric IL-10-producing CD5+ B cells suppress cow’s milk casein-induced allergic responses in mice. Scientific Reports. 2016 Jan 20;6:19685.
6. Kim, H.S., Kim, A.R., Kim, D.K., Kim, H.W., Park, Y.H., Jang, G.H., Kim, B., Park, Y.M., You, J.S., Kim, H.S., Beaven, M.A., Kim, Y.M., Choi, W.S. Interleukin-10-producing CD5+ B cells inhibit mast cells during immunoglobulin E-mediated allergic responses. Science Signaling. 2015 Mar 17;8:ra28.
7. Lee, D.Y., Kim, H.S., Won, K.J., Lee, K.P., Jung, S.H., Park, E.S., Choi, W.S., Lee, H.M., Kim, B. DJ-1 regulates the expression of renal (pro)renin receptor via reactive oxygen species-mediated epigenetic modification. Biochimica et Biophysica Acta-General Subjects. 2015 Feb;1850:426-34.
8. Kim, T.H., Kim, H.S., Kang, Y.J., Yoon, S., Lee, J., Choi, W.S., Jung, J.H., Kim, H.S. Psammaplin A induces Sirtuin 1-dependent autophagic cell death in doxorubicin-resistant MCF-7/adr human breast cancer cells and xenografts. Biochimica et Biophysica Acta-General Subjects. 2015 Feb;1850:401-10.
9. Kim, D.K., Kim, H.S., Kim, A.R., Jang, G.H., Kim, H.W., Park, Y.H., Kim, B., Park, Y.M., Beaven, M.A., Kim, Y.M., Choi, W.S. The Scaffold Protein Prohibitin Is Required for Antigen-Stimulated Signaling in Mast Cells. Science Signaling. 2013 Sep 10;6:ra80.
10. Kim, D.K., Kim, H.S., Kim, A.R., Kim, J.H., Kim, B., Noh, G., Kim, H.S., Beaven, M.A., Kim, Y.M., Choi, W.S. DJ-1 regulates mast cell activation and IgE-mediated allergic responses. Journal of Allergy and Clinical Immunology. 2013 Jun;131(6):1653-62

<style> p{ font-family: } .p1 { font-size:14px; line-height:150%; } .p2 { font-size:17px; line-height:150%; } </style> <h2 class="bullet">Professor Hyuk-Soon Kim, PhD</h2> <br><br> <img width="186" height="240" src="/sites/bk4health/images/210709_02.png"></p><br><br> <p class="p1">Biographical Information<br><br> Hyuk Soon Kim attended the Konkuk University obtaining a B.Sc. in Biochemistry, M.Sc., and Ph.D. in Medicine. He worked as an assistant professor at School of Medicine, Konkuk Universityin Seoul, Korea (2013 - 2020) and is currently employed as an assistant professor in the Graduate School of Dong-A University in Busan, Korea since 2020. He has published over 45 peer-reviewed papers and several book chapters on immunology and general biology. His current interests are the mechanism of regulatory immune cells, including regulatory T cells (Tregs), regulatory B cells (Bregs), regulatory natural killer cells (NKregs) and regulatory innate lymphoid cells (ILCreg) in various immune disorders as allergy, autoimmune, and cancers.</p><br><br> <p class="p1">Ten selected published papers </p><Br> <ol> <li><strong>Kim, H.S.</strong>, Lee, M.B., Lee, D., Min, K.Y., Koo, J., Kim, H.W., Park, Y.H., Kim, S.J., Kim, Ikutani, M., Takaki, S., Y.M., Choi, W.S. The regulatory B cell-mediated peripheral tolerance maintained by mast cell IL-5 suppresses contact hypersensitivity. Science Advances. 2019 Jul 17;5(7):aav8152.</li> <li>Cho, M., Lee, J.E., Lim, H., Shin, H.W., Khalmuratova, R., Choi, G., <strong>Kim, H.S.</strong>, Choi, W.S., Park, Y.J., Shim, I., Kim, B.S., Kang, C.Y., Kim, J.O., Tanaka, S., Kubo, M., Chung, Y. Fibrinogen-cleavage products and TLR4 promote the generation of programmed cell death 1 ligand 2(PD-L2)+ dendritic cells in allergic asthma. Journal of Allergy and Clinical Immunology. 2018 Aug;142(2):530-541.e6.</li> <li><strong>Kim, H.S.</strong>, Nam, S.T., Mun, S.H., Lee, S.K., Kim, H.W., Park, Y.H. Kim, B., Won, K.J., Kim, H.R., Park, Y.M., Kim, H.S., Beaven, M.A., Kim, Y.M., Choi, W.S. DJ-1 controls bone homeostasis through the regulation of osteoclast. Nature Communications. 2017 Nov 15;8:1519.</li> <li><strong>Kim, H.S.</strong>, Jang, J.H., Lee, M.B., Jung, I.D., Kim, Y.M., Park, Y.M., Choi, W.S. A novel IL-10-producing innate lymphoid cells (ILC10) in a contact hypersensitivity mouse model. BMB Reports. 2016 May;49(5):293-6.</li> <li>Kim, A.R., <strong>Kim, H.S.</strong>, Kim, D.K., Nam, S.T., Kim, H.W., Park, Y.H., Lee, D., Lee, M.B., Lee, J.H., Kim, B., Beaven, M.A., Kim, H.S., Kim, Y.M., Choi, W.S. Mesenteric IL-10-producing CD5+ B cells suppress cow’s milk casein-induced allergic responses in mice. Scientific Reports. 2016 Jan 20;6:19685.</li> <li><strong>Kim, H.S.</strong>, Kim, A.R., Kim, D.K., Kim, H.W., Park, Y.H., Jang, G.H., Kim, B., Park, Y.M., You, J.S., Kim, H.S., Beaven, M.A., Kim, Y.M., Choi, W.S. Interleukin-10-producing CD5+ B cells inhibit mast cells during immunoglobulin E-mediated allergic responses. Science Signaling. 2015 Mar 17;8:ra28.</li> <li>Lee, D.Y., <strong>Kim, H.S.</strong>, Won, K.J., Lee, K.P., Jung, S.H., Park, E.S., Choi, W.S., Lee, H.M., Kim, B. DJ-1 regulates the expression of renal (pro)renin receptor via reactive oxygen species-mediated epigenetic modification. Biochimica et Biophysica Acta-General Subjects. 2015 Feb;1850:426-34.</li> <li>Kim, T.H., <strong>Kim, H.S.</strong>, Kang, Y.J., Yoon, S., Lee, J., Choi, W.S., Jung, J.H., Kim, H.S. Psammaplin A induces Sirtuin 1-dependent autophagic cell death in doxorubicin-resistant MCF-7/adr human breast cancer cells and xenografts. Biochimica et Biophysica Acta-General Subjects. 2015 Feb;1850:401-10.</li> <li>Kim, D.K., <strong>Kim, H.S.</strong>, Kim, A.R., Jang, G.H., Kim, H.W., Park, Y.H., Kim, B., Park, Y.M., Beaven, M.A., Kim, Y.M., Choi, W.S. The Scaffold Protein Prohibitin Is Required for Antigen-Stimulated Signaling in Mast Cells. Science Signaling. 2013 Sep 10;6:ra80.</li> <li>Kim, D.K., <strong>Kim, H.S.</strong>, Kim, A.R., Kim, J.H., Kim, B., Noh, G., Kim, H.S., Beaven, M.A., Kim, Y.M., Choi, W.S. DJ-1 regulates mast cell activation and IgE-mediated allergic responses. Journal of Allergy and Clinical Immunology. 2013 Jun;131(6):1653-62</li> </ol>